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MLYS

Mineralys Therapeutics, Inc.
NasdaqPharmaceutical PreparationsLatest fiscal year ended Dec 31, 2025

Figures below are compared against other companies classified under Pharmaceutical Preparations.

Grades vs. industry

No grades. This company reported an operating loss several times its revenue, so it is treated as pre-commercial and left out of industry comparisons — margins and returns measured against a revenue that barely exists describe a research programme rather than a business. Its reported figures appear in full below.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
Not reported70.7%—
Operating margin
Operating income as a share of revenue.
Not reported-15.3%—
Net margin
Net income as a share of revenue.
Not reported-13.0%—
Free cash flow margin
Free cash flow as a share of revenue.
Not reported-2.0%—
Return on equity
Net income divided by shareholder equity.
-23.9%-14.2%—
Return on assets
Net income divided by total assets.
-23.4%-9.5%—
Return on invested capital
After-tax operating profit over debt plus equity less cash.
-28.4%-6.1%—

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Nothing here is ranked: this company reported an operating loss several times its revenue, so it is left out of its industry’s comparisons and does not count toward the medians shown. Its own figures are exactly as filed.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
Not reported0.43x—
Current ratio
Current assets over current liabilities.
43.76x2.96x—
Quick ratio
Current assets excluding inventory, over current liabilities.
43.76x2.58x—
Interest coverage
Operating income divided by interest expense.
Not reported-0.74x—
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
Not reported-1.25x—

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Nothing here is ranked: this company reported an operating loss several times its revenue, so it is left out of its industry’s comparisons and does not count toward the medians shown. Its own figures are exactly as filed.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 20 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.

DateInsiderTransactionSharesPriceValue
Oct 19, 2026
Peterson Kristine
Director
Grant or award12,400$0.00$0.00
Oct 19, 2026
Peterson Kristine
Director
Grant or award(derivative)16,600$0.00$0.00
Oct 19, 2026
COATS LONNEL
Director
Grant or award12,400$0.00$0.00
Oct 19, 2026
COATS LONNEL
Director
Grant or award(derivative)16,600$0.00$0.00
Sep 30, 2026
Congleton Jon
Chief Executive Officer
Open-market sale75,000$25.46$1.91M
Sep 22, 2026
Slingsby Brian Taylor
Director
Open-market sale104,320$28.81$3.01M
Sep 21, 2026
Warren Eric
Chief Commercial Officer
Open-market sale7,438$28.12$209.1K
Sep 21, 2026
Warren Eric
Chief Commercial Officer
Option exercise7,438$13.24$98.5K
Sep 21, 2026
Warren Eric
Chief Commercial Officer
Option exercise(derivative)7,438$0.00$0.00
Sep 15, 2026
Karydas Daphne
Director
Open-market sale3,000$28.58$85.7K
Sep 15, 2026
Karydas Daphne
Director
Option exercise3,000$12.02$36.1K
Sep 15, 2026
Karydas Daphne
Director
Option exercise(derivative)3,000$0.00$0.00
Aug 21, 2026
Warren Eric
Chief Commercial Officer
Open-market sale7,437$25.98$193.2K
Aug 21, 2026
Warren Eric
Chief Commercial Officer
Option exercise7,437$13.24$98.5K
Aug 21, 2026
Warren Eric
Chief Commercial Officer
Option exercise(derivative)7,437$0.00$0.00
Aug 10, 2026
Rodman David Malcom
Chief Medical Officer
Open-market sale2,170$27.09$58.8K
Aug 10, 2026
Rodman David Malcom
Chief Medical Officer
Option exercise2,170$16.00$34.7K
Aug 10, 2026
Rodman David Malcom
Chief Medical Officer
Option exercise(derivative)2,170$0.00$0.00
Aug 10, 2026
Ferguson James J. III
Chief Medical Officer
Grant or award102,400$0.00$0.00
Aug 10, 2026
Ferguson James J. III
Chief Medical Officer
Grant or award(derivative)135,000$0.00$0.00

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year2025202420232022
Operating income-$170.60M-$192.40M-$84.66M-$31.48M
Net income-$154.65M-$177.81M-$71.90M-$29.80M
EPS (diluted)-$2.29-$3.66-$1.99n/c
Operating cash flow-$142.42M-$166.31M-$81.17M-$29.22M
Capital expenditure$15.0K$96.0K$0.00—
Free cash flow-$142.43M-$166.41M-$81.17M—
Total assets$661.81M$205.90M$251.64M$114.44M
Shareholder equity$646.69M$191.26M$241.15M-$52.27M
Cash$172.92M$114.09M$49.30M$87.70M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from Mineralys Therapeutics, Inc.’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Mar 12, 2026. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.