GPCR
Structure Therapeutics Inc.Figures below are compared against other companies classified under Pharmaceutical Preparations.
Grades vs. industry
Profitability
| Metric | Company | Industry median | Rank |
|---|---|---|---|
Gross margin Gross profit as a share of revenue. Often unreported. | Not reported | 72.1% | — |
Operating margin Operating income as a share of revenue. | Not reported | -34.2% | — |
Net margin Net income as a share of revenue. | Not reported | -30.0% | — |
Free cash flow margin Free cash flow as a share of revenue. | Not reported | -15.3% | — |
Return on equity Net income divided by shareholder equity. | -9.3% | -52.3% | 69 / 368 |
Return on assets Net income divided by total assets. | -8.9% | -37.6% | 88 / 419 |
Return on invested capital After-tax operating profit over debt plus equity less cash. | -19.5% | -49.3% | 74 / 257 |
top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.
“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.
Financial health
| Metric | Company | Industry median | Rank |
|---|---|---|---|
Debt to equity Total debt divided by shareholder equity. | Not reported | 0.24x | — |
Current ratio Current assets over current liabilities. | 24.81x | 4.17x | 18 / 419 |
Quick ratio Current assets excluding inventory, over current liabilities. | 24.81x | 3.84x | 18 / 419 |
Interest coverage Operating income divided by interest expense. | Not reported | -15.21x | — |
Net debt to EBITDA Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed. | Not reported | -1.56x | — |
top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.
“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.
Insider activity
Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 26 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.
| Date | Insider | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|
| Sep 21, 2026 | Coll Crespo Blas CHIEF MEDICAL OFFICER | Open-market sale(derivative) | 4,008 | $36.15 | $144.9K |
| Sep 21, 2026 | Coll Crespo Blas CHIEF MEDICAL OFFICER | Conversion(derivative) | 4,008 | $0.00 | $0.00 |
| Sep 21, 2026 | Coll Crespo Blas CHIEF MEDICAL OFFICER | Conversion | 12,024 | $0.00 | $0.00 |
| Sep 18, 2026 | Coll Crespo Blas CHIEF MEDICAL OFFICER | Withheld for tax | 10,626 | $11.67 | $124.0K |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 4,539 | $47.20 | $214.3K |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 1,300 | $45.86 | $59.6K |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Option exercise | 17,817 | $0.34 | $6.1K |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 100 | $47.83 | $4.8K |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Conversion(derivative) | 5,939 | $0.00 | $0.00 |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Conversion | 17,817 | $0.00 | $0.00 |
| Sep 1, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Option exercise(derivative) | 17,817 | $0.00 | $0.00 |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 3,020 | $53.13 | $160.5K |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 519 | $54.20 | $28.1K |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 400 | $55.05 | $22.0K |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Option exercise | 11,817 | $0.34 | $4.0K |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Option exercise(derivative) | 11,817 | $0.00 | $0.00 |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Conversion | 11,817 | $0.00 | $0.00 |
| Aug 18, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Conversion(derivative) | 3,939 | $0.00 | $0.00 |
| Aug 6, 2026 | Berrios John Joseph Chief Commercial Officer | Grant or award(derivative) | 174,612 | $0.00 | $0.00 |
| Aug 6, 2026 | Berrios John Joseph Chief Commercial Officer | Grant or award | 140,766 | $0.00 | $0.00 |
| Aug 4, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 3,100 | $49.29 | $152.8K |
| Aug 4, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Open-market sale(derivative) | 839 | $50.03 | $42.0K |
| Aug 4, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Option exercise | 11,817 | $0.34 | $4.0K |
| Aug 4, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Option exercise(derivative) | 11,817 | $0.00 | $0.00 |
| Aug 4, 2026 | Lin Xichen CHIEF SCIENTIFIC OFFICER | Conversion(derivative) | 3,939 | $0.00 | $0.00 |
A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.
Annual financials
| Fiscal year | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|
| Operating income | -$176.56M | -$158.23M | -$102.78M | -$52.56M |
| Net income | -$141.20M | -$122.53M | -$89.62M | -$51.32M |
| EPS (diluted) | -$0.80 | -$0.78 | -$0.81 | n/c |
| Operating cash flow | -$222.20M | -$116.64M | -$79.49M | -$46.12M |
| Capital expenditure | $3.61M | $1.29M | $2.17M | $155.0K |
| Free cash flow | -$225.81M | -$117.93M | -$81.66M | -$46.27M |
| Total assets | $1.58B | $903.33M | $482.02M | $97.84M |
| Shareholder equity | $1.52B | $864.84M | $452.97M | -$115.14M |
| Cash | $799.62M | $169.51M | $129.79M | $26.09M |
A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.
n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.
Source
Figures come from Structure Therapeutics Inc.’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Feb 26, 2026. View filings on EDGAR.