Lodestar

ANTX

AN2 Therapeutics, Inc.
NasdaqPharmaceutical PreparationsLatest fiscal year ended Dec 31, 2025

Figures below are compared against other companies classified under Pharmaceutical Preparations.

Grades vs. industry

Profitability
D35/100
Ranked against 287 peers using 3 metrics.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
Not reported68.6%—
Operating margin
Operating income as a share of revenue.
Not reported-31.8%—
Net margin
Net income as a share of revenue.
Not reported-30.0%—
Free cash flow margin
Free cash flow as a share of revenue.
Not reported-14.7%—
Return on equity
Net income divided by shareholder equity.
-66.3%-49.7%248 / 416
Return on assets
Net income divided by total assets.
-56.8%-37.5%308 / 474
Return on invested capital
After-tax operating profit over debt plus equity less cash.
-90.9%-45.2%203 / 287

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
Not reported0.25x—
Current ratio
Current assets over current liabilities.
6.87x3.99x148 / 472
Quick ratio
Current assets excluding inventory, over current liabilities.
6.87x3.62x145 / 472
Interest coverage
Operating income divided by interest expense.
Not reported-11.95x—
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
Not reported-1.25x—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. 1 of the last 16 reported transactions were open-market purchases; the rest are mostly sales and compensation.

DateInsiderTransactionSharesPriceValue
Oct 12, 2026
Aziz Kabeer
Director
Grant or award2,465$0.00$0.00
Oct 12, 2026
Martin Patricia A.
Director
Grant or award389$0.00$0.00
Oct 12, 2026
Marks Gilbert Lynn
Director
Grant or award2,283$0.00$0.00
Sep 15, 2026
Trenor Cameron C. III
Chief Medical Officer
Grant or award116,667$0.00$0.00
Sep 15, 2026
Trenor Cameron C. III
Chief Medical Officer
Grant or award(derivative)233,333$0.00$0.00
Sep 9, 2026
Readnour Robin Shane
Director
Open-market sale585$6.02$3.5K
Sep 9, 2026
Readnour Robin Shane
Director
Open-market sale523$6.02$3.2K
Sep 8, 2026
Readnour Robin Shane
Director
Open-market sale5,294$6.02$31.9K
Sep 8, 2026
Readnour Robin Shane
Director
Open-market sale4,725$6.02$28.4K
Sep 3, 2026
Readnour Robin Shane
Director
Open-market sale3,223$6.07$19.6K
Sep 3, 2026
Readnour Robin Shane
Director
Open-market sale2,877$6.07$17.5K
Sep 1, 2026
FitzPatrick Margaret M
Director
Open-market purchase2,098$5.53$11.6K
Sep 1, 2026
Williams Sarah Joanne
Principal Accounting Officer
Open-market sale272$5.53$1.5K
Aug 17, 2026
Readnour Robin Shane
Director
Open-market sale18,706$6.01$112.4K
Aug 17, 2026
Readnour Robin Shane
Director
Open-market sale16,696$6.01$100.3K
Aug 14, 2026
Zakrzewski Joseph S
Director
Gift405,880$0.00$0.00

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year20252024202320222021
Operating income-$38.11M-$56.79M-$69.64M-$42.26M-$21.57M
Net income-$35.17M-$51.32M-$64.73M-$40.96M-$21.54M
EPS (diluted)-$1.16-$1.72-$2.74n/cn/c
Operating cash flow-$29.83M-$49.26M-$53.29M-$33.46M-$20.48M
Total assets$61.95M$92.09M$138.74M$102.56M$65.32M
Shareholder equity$53.06M$81.85M$124.70M$95.37M-$47.41M
Cash$19.94M$21.35M$15.65M$27.22M$12.10M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from AN2 Therapeutics, Inc.’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Mar 17, 2026. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.