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ANRO

Alto Neuroscience, Inc.
NYSEPharmaceutical PreparationsLatest fiscal year ended Dec 31, 2025

Figures below are compared against other companies classified under Pharmaceutical Preparations.

Grades vs. industry

Financial health
B+71/100
Ranked against 133 peers using 4 metrics.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
Not reported68.6%—
Operating margin
Operating income as a share of revenue.
Not reported-31.8%—
Net margin
Net income as a share of revenue.
Not reported-30.0%—
Free cash flow margin
Free cash flow as a share of revenue.
Not reported-14.7%—
Return on equity
Net income divided by shareholder equity.
-41.8%-49.7%186 / 416
Return on assets
Net income divided by total assets.
-34.2%-37.5%221 / 474
Return on invested capital
After-tax operating profit over debt plus equity less cash.
Not reported-45.2%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
0.11x0.25x48 / 133
Current ratio
Current assets over current liabilities.
15.69x3.99x44 / 472
Quick ratio
Current assets excluding inventory, over current liabilities.
15.69x3.62x44 / 472
Interest coverage
Operating income divided by interest expense.
-26.88x-11.95x119 / 191
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
Not reported-1.25x—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Debt figures can be understated where a filer splits borrowings across XBRL tags this site does not match.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 11 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.

DateInsiderTransactionSharesPriceValue
Oct 2, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise55,000$2.32$127.6K
Oct 2, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise(derivative)55,000$0.00$0.00
Sep 30, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Open-market sale23,170$25.78$597.3K
Sep 30, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise24,056$2.35$56.5K
Sep 30, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Open-market sale886$26.87$23.8K
Sep 30, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise(derivative)24,056$0.00$0.00
Sep 29, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Open-market sale110,830$26.58$2.95M
Sep 29, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise56,455$2.35$132.7K
Sep 29, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise54,375$2.35$127.8K
Sep 29, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise(derivative)56,455$0.00$0.00
Sep 29, 2026
Smith Nicholas Conrad
PRESIDENT AND CFO
Option exercise(derivative)54,375$0.00$0.00

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year202520242023
Operating income-$66.36M-$68.61M-$37.81M
Net income-$63.24M-$61.43M-$36.30M
EPS (diluted)-$2.19-$2.50n/c
Operating cash flow-$51.77M-$47.42M-$33.45M
Capital expenditure$24.0K$2.08M$470.0K
Free cash flow-$51.79M-$49.50M-$33.92M
Total assets$184.69M$177.54M$86.63M
Shareholder equity$151.14M$151.46M-$71.67M
Total debt$16.76M$10.25M$9.86M
Cash$176.48M$168.23M$82.55M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from Alto Neuroscience, Inc.’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Mar 16, 2026. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.