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LYEL

Lyell Immunopharma, Inc.
NasdaqPharmaceutical PreparationsLatest fiscal year ended Dec 31, 2025

Lyell Immunopharma, Inc. reported revenue of $36.0K in its most recent fiscal year, down 41.0% on the year before. It kept -762355.6% of that as net income, and generated -$150.80M of free cash flow. Figures below are compared against other companies classified under Pharmaceutical Preparations.

Grades vs. industry

Growth
F7/100
Ranked against 169 peers using 3 metrics.
Profitability
F26/100
Ranked against 257 peers using 3 metrics.

Growth

MetricCompanyIndustry medianRank
Revenue growth (YoY)
Latest fiscal year revenue vs. the year before.
-41.0%7.4%173 / 219
Revenue growth (3y)
Annualized revenue growth over three fiscal years.
-92.5%7.6%186 / 186
Revenue growth (5y)
Annualized revenue growth over five fiscal years.
-65.9%7.3%169 / 169
EPS growth (YoY)
Diluted EPS vs. the prior fiscal year.
Not reported-33.3%—
EPS growth (3y)
Annualized diluted EPS growth over three fiscal years.
Not reported4.0%—
EPS growth (5y)
Annualized diluted EPS growth over five fiscal years.
Not reported3.8%—
Free cash flow growth (YoY)
Operating cash flow less capital expenditure, vs. prior year.
Not reported-7.9%—
Free cash flow growth (3y)
Annualized free cash flow growth over three fiscal years.
Not reported1.4%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
Not reported72.1%—
Operating margin
Operating income as a share of revenue.
-748344.4%-34.2%—
Net margin
Net income as a share of revenue.
-762355.6%-30.0%—
Free cash flow margin
Free cash flow as a share of revenue.
-418900.0%-15.3%—
Return on equity
Net income divided by shareholder equity.
-110.6%-52.3%265 / 368
Return on assets
Net income divided by total assets.
-80.7%-37.6%309 / 419
Return on invested capital
After-tax operating profit over debt plus equity less cash.
-113.2%-49.3%195 / 257

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
Not reported0.24x—
Current ratio
Current assets over current liabilities.
5.28x4.17x169 / 419
Quick ratio
Current assets excluding inventory, over current liabilities.
5.28x3.84x169 / 419
Interest coverage
Operating income divided by interest expense.
Not reported-15.21x—
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
Not reported-1.56x—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 12 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.

DateInsiderTransactionSharesPriceValue
Oct 12, 2026
Aguirre Jarrad Mattieu
Chief Medical Officer
Open-market sale422$8.63$3.6K
Sep 10, 2026
Shook David
Chief Medical Officer
Open-market sale500$12.70$6.3K
Sep 10, 2026
Aguirre Jarrad Mattieu
Chief Medical Officer
Grant or award(derivative)47,500$0.00$0.00
Aug 21, 2026
Seely Lynn
President and CEO
Open-market sale9,589$15.54$149.0K
Aug 21, 2026
Lee Gary K.
Chief Scientific Officer
Open-market sale1,457$15.54$22.6K
Aug 21, 2026
Hill Stephen J.
Chief Operating Officer
Open-market sale989$15.54$15.4K
Aug 10, 2026
Bulis Veronica Sanchez
VP, Corporate Controller
Open-market sale621$14.34$8.9K
Aug 10, 2026
Seely Lynn
President and CEO
Open-market sale390$14.34$5.6K
Aug 10, 2026
Lee Gary K.
Chief Scientific Officer
Open-market sale131$14.34$1.9K
Aug 10, 2026
Hill Stephen J.
Chief Operating Officer
Open-market sale89$14.34$1.3K
Jul 27, 2026
Innovative Cellular Therapeutics Holdings Ltd
10% owner
Other38,500$0.00$0.00
Jul 27, 2026
Innovative Cellular Therapeutics Holdings Ltd
10% owner
Other44,000$0.00$0.00

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year2025202420232022202120202019
Revenue$36.0K$61.0K$130.0K$84.68M$10.65M$7.76M$657.0K
Operating income-$269.40M-$358.75M-$247.01M-$187.06M-$214.78M-$211.94M-$102.09M
Net income-$274.45M-$342.99M-$234.63M-$183.12M-$250.22M-$204.47M-$129.38M
EPS (diluted)-$16.06-$26.23-$18.70n/cn/cn/cn/c
Operating cash flow-$150.02M-$162.39M-$163.69M-$169.56M-$126.25M-$160.87M$39.47M
Capital expenditure$780.0K$464.0K$2.69M$24.28M$65.50M$51.48M$16.05M
Free cash flow-$150.80M-$162.86M-$166.38M-$193.83M-$191.75M-$212.35M$23.43M
Total assets$340.05M$490.86M$750.03M$937.56M$1.13B$908.28M—
Shareholder equity$248.20M$382.82M$654.95M$833.25M$929.79M-$292.53M-$111.11M
Cash$60.18M$105.60M$145.65M$123.55M$293.83M$140.41M$96.67M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from Lyell Immunopharma, Inc.’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Mar 12, 2026. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.