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ANAB

ANAPTYSBIO, INC
NasdaqPharmaceutical PreparationsLatest fiscal year ended Dec 31, 2025

ANAPTYSBIO, INC reported revenue of $234.60M in its most recent fiscal year, up 157.0% on the year before. It kept -5.6% of that as net income, and generated $19.61M of free cash flow. Figures below are compared against other companies classified under Pharmaceutical Preparations.

Grades vs. industry

Growth
A86/100
Ranked against 192 peers using 3 metrics.
Profitability
B+74/100
Ranked against 179 peers using 5 metrics.
Financial health
B67/100
Ranked against 56 peers using 3 metrics.

Growth

MetricCompanyIndustry medianRank
Revenue growth (YoY)
Latest fiscal year revenue vs. the year before.
157.0%7.7%28 / 250
Revenue growth (3y)
Annualized revenue growth over three fiscal years.
183.6%8.8%10 / 212
Revenue growth (5y)
Annualized revenue growth over five fiscal years.
25.6%7.5%50 / 192
EPS growth (YoY)
Diluted EPS vs. the prior fiscal year.
Not reported-10.0%—
EPS growth (3y)
Annualized diluted EPS growth over three fiscal years.
Not reported-1.6%—
EPS growth (5y)
Annualized diluted EPS growth over five fiscal years.
Not reported1.9%—
Free cash flow growth (YoY)
Operating cash flow less capital expenditure, vs. prior year.
Not reported-7.9%—
Free cash flow growth (3y)
Annualized free cash flow growth over three fiscal years.
Not reported1.4%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
Not reported68.6%—
Operating margin
Operating income as a share of revenue.
96.7%-31.8%1 / 187
Net margin
Net income as a share of revenue.
-5.6%-30.0%78 / 199
Free cash flow margin
Free cash flow as a share of revenue.
8.4%-14.7%56 / 179
Return on equity
Net income divided by shareholder equity.
-35.6%-49.7%168 / 416
Return on assets
Net income divided by total assets.
-3.6%-37.5%89 / 474
Return on invested capital
After-tax operating profit over debt plus equity less cash.
Not reported-45.2%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
Not reported0.25x—
Current ratio
Current assets over current liabilities.
9.07x3.99x107 / 472
Quick ratio
Current assets excluding inventory, over current liabilities.
9.07x3.62x107 / 472
Interest coverage
Operating income divided by interest expense.
Not reported-11.95x—
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
-0.93x-1.25x30 / 56

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Debt figures can be understated where a filer splits borrowings across XBRL tags this site does not match.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 7 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.

DateInsiderTransactionSharesPriceValue
Oct 1, 2026
RENTON HOLLINGS
Director
Open-market sale5,000$49.87$249.4K
Oct 1, 2026
RENTON HOLLINGS
Director
Option exercise5,000$18.03$90.2K
Oct 1, 2026
RENTON HOLLINGS
Director
Option exercise(derivative)5,000$0.00$0.00
Sep 15, 2026
Orwin John A
Director
Option exercise1,300$0.00$0.00
Sep 15, 2026
Orwin John A
Director
Option exercise(derivative)1,300$0.00$0.00
Mar 12, 2026
Faga Daniel
President, CEO
Grant or award(derivative)53,334$0.00$0.00
Mar 12, 2026
Lizzul Paul F.
Chief Medical Officer
Grant or award(derivative)16,667$0.00$0.00

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year2025202420232022202120202019201820172016
Revenue$234.60M$91.28M$17.16M$10.29M$63.17M$75.00M$8.00M$5.00M$10.00M$16.68M
Operating income$226.90M$66.15M-$164.41M-$115.15M-$56.81M-$23.88M-$107.43M-$66.72M-$28.78M-$3.02M
Net income-$13.23M-$145.23M-$163.62M-$128.72M-$57.80M-$19.93M-$97.34M-$61.66M-$30.07M-$4.26M
EPS (diluted)-$0.44-$4.92-$6.08-$4.57-$2.11-$0.73-$3.60-$2.50-$1.52n/c
Operating cash flow$19.70M-$135.34M-$120.80M-$73.59M-$45.92M-$14.16M-$69.52M-$48.51M-$19.44M-$9.03M
Capital expenditure$87.0K$358.0K$807.0K$358.0K$1.37M$569.0K$805.0K$1.06M$290.0K$50.0K
Free cash flow$19.61M-$135.69M-$121.61M-$73.95M-$47.29M-$14.73M-$70.32M-$49.57M-$19.73M-$9.08M
Total assets$364.39M$483.83M$452.39M$610.38M$643.07M$416.55M$435.20M$509.00M$329.36M$62.18M
Shareholder equity$37.21M$70.87M$88.10M$262.10M$356.43M$396.73M$405.01M$486.37M$307.58M-$38.25M
Cash$138.20M$23.08M$35.97M$71.31M$495.73M$250.46M$171.02M$113.60M$81.19M$51.23M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from ANAPTYSBIO, INC’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-KT filed Sep 21, 2026. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.