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TWST

Twist Bioscience Corp
NasdaqBiological Products, (No Diagnostic Substances)Latest fiscal year ended Sep 30, 2025

Twist Bioscience Corp reported revenue of $376.57M in its most recent fiscal year, up 20.3% on the year before. It kept -20.6% of that as net income, and generated -$75.63M of free cash flow. Figures below are compared against other companies classified under Biological Products, (No Diagnostic Substances).

Grades vs. industry

Growth
B67/100
Ranked against 57 peers using 3 metrics.
Profitability
B61/100
Ranked against 42 peers using 7 metrics.

Growth

MetricCompanyIndustry medianRank
Revenue growth (YoY)
Latest fiscal year revenue vs. the year before.
20.3%9.4%34 / 82
Revenue growth (3y)
Annualized revenue growth over three fiscal years.
22.8%5.0%21 / 65
Revenue growth (5y)
Annualized revenue growth over five fiscal years.
33.1%7.7%16 / 57
EPS growth (YoY)
Diluted EPS vs. the prior fiscal year.
Not reported0.0%—
EPS growth (3y)
Annualized diluted EPS growth over three fiscal years.
Not reported1.8%—
EPS growth (5y)
Annualized diluted EPS growth over five fiscal years.
Not reported3.9%—
Free cash flow growth (YoY)
Operating cash flow less capital expenditure, vs. prior year.
Not reported-30.7%—
Free cash flow growth (3y)
Annualized free cash flow growth over three fiscal years.
Not reported14.1%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
50.7%66.5%29 / 42
Operating margin
Operating income as a share of revenue.
-36.2%-94.6%25 / 55
Net margin
Net income as a share of revenue.
-20.6%-26.5%26 / 56
Free cash flow margin
Free cash flow as a share of revenue.
-20.1%-74.1%20 / 53
Return on equity
Net income divided by shareholder equity.
-16.4%-55.7%23 / 110
Return on assets
Net income divided by total assets.
-12.1%-43.7%31 / 137
Return on invested capital
After-tax operating profit over debt plus equity less cash.
-37.1%-59.5%29 / 74

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
Not reported0.29x—
Current ratio
Current assets over current liabilities.
3.64x5.03x86 / 137
Quick ratio
Current assets excluding inventory, over current liabilities.
3.33x4.84x88 / 137
Interest coverage
Operating income divided by interest expense.
Not reported-12.13x—
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
Not reported-1.02x—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 40 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.

DateInsiderTransactionSharesPriceValue
Oct 9, 2026
Laponis Adam
Chief Financial Officer
Open-market sale2,462$156.30$384.8K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale1,840$200.44$368.8K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale1,017$202.32$205.8K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale481$201.26$96.8K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale432$203.61$88.0K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale297$205.78$61.1K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale290$204.80$59.4K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale146$206.84$30.2K
Oct 5, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale45$207.46$9.3K
Oct 2, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale45,736$188.88$8.64M
Oct 2, 2026
Finn Patrick John
President and COO
Open-market sale25,714$188.88$4.86M
Oct 2, 2026
Green Paula
SVP of Human Resources
Open-market sale10,088$188.88$1.91M
Oct 2, 2026
Cho Dennis
See Remarks
Open-market sale9,514$188.88$1.80M
Oct 2, 2026
Laponis Adam
Chief Financial Officer
Open-market sale8,057$188.88$1.52M
Oct 2, 2026
WERNER ROBERT F.
Chief Accounting Officer
Open-market sale1,482$188.88$279.9K
Oct 1, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale655$200.00$131.0K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale2,485$175.23$435.4K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale945$176.39$166.7K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale515$180.39$92.9K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale501$183.76$92.1K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale330$178.67$59.0K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale164$177.17$29.1K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale143$179.93$25.7K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale83$184.60$15.3K
Sep 24, 2026
Leproust Emily M.
Chief Executive Officer
Open-market sale21$181.45$3.8K

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year202520242023202220212020201920182017
Revenue$376.57M$312.97M$245.11M$203.56M$132.33M$90.10M$54.38M$25.43M$10.77M
Operating income-$136.26M-$220.83M-$217.16M-$234.78M-$152.73M-$140.08M-$108.85M-$70.56M-$58.48M
Net income-$77.67M-$208.73M-$204.62M-$217.86M-$152.10M-$139.93M-$107.67M-$71.24M-$59.31M
EPS (diluted)-$1.30-$3.60-$3.60-$4.04-$3.15-$3.57-$3.92n/cn/c
Operating cash flow-$47.63M-$64.09M-$142.47M-$124.39M-$112.24M-$142.25M-$87.94M-$66.16M-$51.30M
Capital expenditure$28.00M$5.08M$27.78M$101.86M$27.06M$9.87M$14.76M$3.69M$6.59M
Free cash flow-$75.63M-$69.17M-$170.25M-$226.24M-$139.31M-$152.12M-$102.69M-$69.85M-$57.90M
Total assets$641.86M$614.32M$776.40M$961.38M$702.10M$398.88M$186.99M$115.79M—
Shareholder equity$472.96M$472.69M$623.43M$789.38M$580.82M$336.26M$152.08M-$201.42M-$133.36M
Total debt———$0.00$1.55M$4.74M$7.73M$9.72M—
Cash$183.05M$226.32M$286.47M$378.69M$465.83M$93.67M$46.73M$80.76M$31.23M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from Twist Bioscience Corp’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Nov 17, 2025. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.