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Clene Inc.
NasdaqPharmaceutical PreparationsLatest fiscal year ended Dec 31, 2025

Clene Inc. reported revenue of $200.0K in its most recent fiscal year, down 41.5% on the year before. It kept -13086.5% of that as net income, and generated -$18.59M of free cash flow. Figures below are compared against other companies classified under Pharmaceutical Preparations.

Grades vs. industry

No grades available. Grades compare a company against others sharing its industry classification, and this one does not have enough classified peers with reported figures to support a meaningful comparison.

Growth

MetricCompanyIndustry medianRank
Revenue growth (YoY)
Latest fiscal year revenue vs. the year before.
-41.5%12.8%—
Revenue growth (3y)
Annualized revenue growth over three fiscal years.
-24.9%12.2%—
Revenue growth (5y)
Annualized revenue growth over five fiscal years.
-0.6%12.5%—
EPS growth (YoY)
Diluted EPS vs. the prior fiscal year.
Not reported-1.4%—
EPS growth (3y)
Annualized diluted EPS growth over three fiscal years.
Not reported0.6%—
EPS growth (5y)
Annualized diluted EPS growth over five fiscal years.
Not reported0.0%—
Free cash flow growth (YoY)
Operating cash flow less capital expenditure, vs. prior year.
Not reported-4.1%—
Free cash flow growth (3y)
Annualized free cash flow growth over three fiscal years.
Not reported1.4%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Profitability

MetricCompanyIndustry medianRank
Gross margin
Gross profit as a share of revenue. Often unreported.
78.5%70.7%—
Operating margin
Operating income as a share of revenue.
-11541.5%-15.3%—
Net margin
Net income as a share of revenue.
-13086.5%-13.0%—
Free cash flow margin
Free cash flow as a share of revenue.
-9292.5%-2.0%—
Return on equity
Net income divided by shareholder equity.
Not reported-14.2%—
Return on assets
Net income divided by total assets.
-144.4%-9.5%—
Return on invested capital
After-tax operating profit over debt plus equity less cash.
Not reported-6.1%—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Financial health

MetricCompanyIndustry medianRank
Debt to equity
Total debt divided by shareholder equity.
Not reported0.43x—
Current ratio
Current assets over current liabilities.
0.83x2.96x—
Quick ratio
Current assets excluding inventory, over current liabilities.
0.83x2.58x—
Interest coverage
Operating income divided by interest expense.
-8.61x-0.74x—
Net debt to EBITDA
Net debt over derived EBITDA. EBITDA is not a GAAP tag; it is computed.
Not reported-1.25x—

top third of peersmiddle thirdbottom third. Rank 1 is always best — for debt and payout ratios that means the lowest figure, not the highest.

“Not reported” means the company did not tag this figure in its filing, not that the value is zero. Rankings are hidden where fewer than 5 classified peers reported the metric, and compare against a broad industry code rather than close competitors.

Insider activity

Trades reported by officers, directors and 10% shareholders on SEC Form 4. None of the last 16 reported transactions were open-market purchases — grants, option exercises and sales make up the majority of insider filings at most companies.

DateInsiderTransactionSharesPriceValue
Oct 20, 2026
BROWN MORGAN R
Chief Financial Officer
Grant or award(derivative)20,000$0.00$0.00
Oct 20, 2026
Mortenson Mark
Chief Science Officer
Grant or award(derivative)30,000$0.00$0.00
Oct 20, 2026
Etherington Robert Dee
President & CEO
Grant or award(derivative)55,000$0.00$0.00
Sep 16, 2026
MATLIN DAVID J
Director
Grant or award434,451$3.28$1.42M
Sep 16, 2026
Mosca Alison
Director, 10% owner
Grant or award198,171$3.28$650.0K
Sep 16, 2026
Etherington Robert Dee
President & CEO
Grant or award15,244$3.28$50.0K
Aug 13, 2026
MATLIN DAVID J
Director
Grant or award(derivative)6,230$0.00$0.00
Aug 13, 2026
WILCOX REED N
Director
Grant or award(derivative)3,514$0.00$0.00
Aug 13, 2026
McLaughlin Vallerie
Director
Grant or award(derivative)3,514$0.00$0.00
Aug 13, 2026
Gay Jonathon
Director
Grant or award(derivative)3,794$0.00$0.00
Aug 13, 2026
Jacobovitz Shalom
Director
Grant or award(derivative)4,752$0.00$0.00
Aug 13, 2026
Mosca Alison
Director
Grant or award(derivative)4,872$0.00$0.00
Aug 13, 2026
Desai Arjun JJ
Director
Grant or award(derivative)3,674$0.00$0.00
Aug 13, 2026
Kiernan Matthew
Director
Grant or award(derivative)3,195$0.00$0.00
Jul 17, 2026
Ugwumba Chidozie
10% owner
Other(derivative)375,000——
Jul 17, 2026
Ugwumba Chidozie
10% owner
Other(derivative)424,358——

A dash under price or value means none was reported, which is normal for grants and gifts — it does not mean the shares were free. Option exercises and awards are compensation arriving on a schedule, not a judgement about the stock.

Annual financials

Fiscal year2025202420232022202120202019
Revenue$200.0K$342.0K$654.0K$473.0K$723.0K$206.0K—
Operating income-$23.08M-$33.09M-$40.54M-$48.41M-$49.98M-$20.21M-$16.33M
Net income-$26.17M-$39.40M-$49.50M-$29.92M-$9.74M-$19.28M-$16.16M
EPS (diluted)————-$0.16n/cn/c
Operating cash flow-$18.55M-$21.33M-$30.17M-$39.01M-$34.62M-$18.93M-$13.20M
Capital expenditure$39.0K$15.0K$330.0K$5.18M$1.33M$387.0K$294.0K
Free cash flow-$18.59M-$21.34M-$30.50M-$44.19M-$35.96M-$19.32M-$13.49M
Total assets$18.13M$27.34M$52.34M$44.49M$63.06M$68.24M$14.88M
Shareholder equity-$17.59M-$8.86M$13.39M$3.24M$12.60M$341.0K-$67.77M
Total debt$17.79M———$13.70M$5.92M—
Cash$5.19M$12.15M$28.82M$18.33M$50.29M$59.27M$8.79M

A dash means the figure was not tagged in that year’s filing. It does not mean zero. Figures reflect the most recent filing covering each period, so restated years show their restated values.

n/c marks per-share figures that are not comparable. Companies report each year as their filings stated it, and an annual report restates only its two prior years — so after a stock split, older years remain on the pre-split share count. Totals above are unaffected.

Source

Figures come from Clene Inc.’s filings with the SEC, as submitted in XBRL. The most recent annual figures are from a 10-K filed Mar 17, 2026. View filings on EDGAR.

Not financial advice. This page presents figures reported to the SEC and compares them with other companies sharing an industry classification. It is not a recommendation to buy or sell anything, and the grades cannot capture everything that matters about a business. Industry classifications are coarse, filings are self-reported, and some figures are missing or understated where companies tag them in ways this site does not match. Do your own research.